Anti-Seasonal H1N1 Nucleocapsid Protein antibody produced in rabbit

Seasonal H1N1 Nucleocapsid Protein Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. The influenza A virus polymerase transcribes and replicates eight virion RNA (vRNA) segments, among which the nucleocapsid protein (NP), thought to control whether mRNA or cRNA is produced. The nucleoprotein (NP), which has multiple functions during the virus life cycle, possesses regions that are highly conserved among influenza A, B, and C viruses. It was recently found several NP mutations that affected the efficient incorporation of multiple viral-RNA (vRNA) segments into progeny virions even though a single vRNA segment was incorporated efficiently. This indicates that the respective conserved amino acids in NP may be critical for the assembly and/or incorporation of sets of eight vRNA segments.

NP antibody was raised against a synthetic peptide from the seasonal H1N1 NP protein.The immunogen is located within amino acids 350 - 400 of Seasonal H1N1 Nucleocapsid Protein.

NP antibody can be used for the detection of the NP protein from the H1N1 strain of Seasonal Influenza A in ELISA.

Supplied in PBS containing 0.02% sodium azide.