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Merck
CN

SAB4100011

Monoclonal Anti-NPR3 antibody produced in mouse

culture supernatant

别名:

Anti-ANPRC, Anti-Aatriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), Anti-GUCY2B, Anti-NPRC

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

NPR3-A15, monoclonal

form

aqueous solution

mol wt

antigen 59.8 kDa

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG2b

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... NPR3(4883)

General description

Natriuretic peptide receptor 3 (NPR3) is a natriuretic peptide receptor. It is expressed in endothelial cells, vessels, endocrine glands, lungs and kidneys. The gene encoding NPR3 is localized on human chromosome 5p14-p13. The protein consists of a 450-amino acid extracellular ligand-binding domain, a transmembrane region and a cytoplasmic tail.

Immunogen

NPR3 purified recombinant protein

Biochem/physiol Actions

Natriuretic peptide receptor 3 (NPR3) has a role in the clearance of natriuretic peptides and modulates their plasma levels. It is associated with essential hypertension. NPR3 may be involved in signaling pathways and is associated with inhibitory G protein.

Physical form

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Attenuated atrial natriuretic peptide-mediated
lipolysis in subcutaneous adipocytes of obese
type 2 diabetic men
Kenneth Verboven
Clinical Science (2016)
Natriuretic peptide receptor-3 gene (NPR3): nonsynonymous polymorphism results in significant reduction in protein expression because of accelerated degradation.
Pereira NL
Circulation. Cardiovascular Genetics (2013)
Association of NPRA and NPRC gene variants and hypertension in Mongolian population.
Chang PY
Genetics and molecular research : GMR (2015)
NPR-C gene polymorphism is associated with increased susceptibility to coronary artery disease in Chinese Han population: a multicenter study.
Hu Q
Oncotarget (2016)

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