生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen ~95 kDa
种属反应性
human, mouse
包装
antibody small pack of 25 μL
浓度
~1.0 mg/mL
技术
immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded mouse testis and biotin / ExtrAvidinTM-Peroxidase staining system.
western blot: 1-2 μg/mL using lysates of HEK-293Tcells over expressing human PIWIL1.
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PIWIL1(9271)
一般描述
The PIWI-like protein 1 (PIWIL1) belongs to the Piwi subfamily.gene is mapped to human chromosome 12q24.33. It is expressed in the cytosol of spermatocytes and spermatids. PIWI-like protein 1 (PIWIL1) is also an Argonaute protein family member.
应用
Anti-PIWIL1 antibody produced in rabbit has been used in western blotting and immunohistochemistry.
生化/生理作用
Anti-PIWIL1 recognizes human and mouse PIWIL1.
The PIWI-like protein 1 (PIWIL1) mediates spermatogenesis. Its aberrant expression favors tumor progression inadenocarcinoma. PIWI-like protein 1 (PIWIL1) plays a key role in embryogenesis, differentiation, stem cell proliferation, growth, and development. High levels of PIWIL1 expression is implicated in the colorectal cancer invasion.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
制备说明
Store at –20 °C. For continuous use, the product may be stored at 2–8 °C for up to one month. For extended storage, freeze at –20 °C in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Circ_101064 regulates the proliferation, invasion and migration of glioma cells through miR-154-5p/PIWIL1 axis
Zhou H, et al.
Biochemical and biophysical research communications, 523(3), 608-614 (2020)
Cancer-testis gene PIWIL 1 promotes cell proliferation, migration, and invasion in lung adenocarcinoma
Xie K, et al.
Cancer medicine, 7(1), 157-166 (2018)
Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells
Liu X, et al.
International Journal of Cancer. Journal International Du Cancer, 118(8), 1922-1929 (2006)
Expression status of PIWIL1 as a prognostic marker of colorectal cancer
Sun R, et al.
Disease Markers, 2017(1) (2017)
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