Anti-Importin 7 (C-terminal) antibody produced in rabbit

In human cells, there are more than 20 members of the importins/exportins family. Importin 7 (also known as IPO7, RANBP7 and IMP7) has been identified as an importin for ribosomal protein L23a (rpL23a), histone H1, human immunodeficiency virus (HIV) reverse transcriptase complex and the zinc finger protein, EZI.

synthetic peptide corresponding to amino acids 943-957 of human Importin 7

Anti-Importin 7 (C-terminal) antibody produced in rabbit has been used in immunoblotting and immunoprecipitation.

Nucleocytoplasmic transport of proteins and RNAs is mediated through nuclear pore complexes (NPCs) and by karyopherins nuclear transport receptors (importins/exportins). Importins mediate either the nuclear import of a very diverse set of protein or RNA cargoes. The function of importins areregulated by the Ran G protein., Ran G protein stimulates the release of cargo from importins. Importins are implicated in anti-aggregation activity of highly basic cargo like histones and ribosomal proteins and in preventing their undesired interactions with other cellular components.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

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