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Merck
CN

SAB4200168

Anti-Importin 4 (N-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

别名:

Anti-IPO4, Anti-Ran-binding protein 4, Anti-imp4b, Anti-ranBP4

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IP, WB
Citations:
2
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~120 kDa

species reactivity

human

concentration

~1.0 mg/mL

technique(s)

immunoprecipitation (IP): 2.5-5.0 μg using HepG2 cell lysates, indirect immunofluorescence: 1.25-2.5 μg/mL using HEK-293T cells overexpressing human Importin 4, western blot: 1-2 μg/mL using HepG2 cell lysates

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IPO4(79711)

General description

Importin 4 is a member of importin protein family. It is a 119 kDa protein.

Immunogen

synthetic peptide corresponding to a sequence at the N-terminal of human Importin 4

Application

Anti-Importin 4 (N-terminal) antibody produced in rabbit has been used in several immunochemical techniques including immunoblotting, immunoprecipitation and immunofluorescence.

Biochem/physiol Actions

Importins can mediate the nuclear import of a diverse set of protein or RNA cargoes. Importins were implicated in anti-aggregation activity of highly basic cargo like histones and ribosomal proteins and in preventing their undesired interactions with other cellular components. It has been identified as an import factor for ribosomal protein rpS3a, the vitamin D receptor (VDR) and the sperm transition protein transition protein 2 (TP2).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容


Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus
Pradeepa MM, et al.
Molecular and Cellular Biology, 28(13), 4331-4341 (2008)
Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains
Jakel S, et al.
The Embo Journal, 21(3), 377-386 (2002)



全球贸易项目编号

货号GTIN
SAB4200168-200UL04061838035097