SAB4200211
Anti-Phospholipase A2 (cPLA2) (N-terminal) antibody produced in rabbit
~1.5 mg/mL, affinity isolated antibody
别名:
Anti-PLA2G4, Anti-PLA2G4A, Anti-cPLA2-alpha, Anti-cytosolic phospholipase A2, group IVA
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~100 kDa
species reactivity
human
packaging
antibody small pack of 25 μL
concentration
~1.5 mg/mL
technique(s)
immunoprecipitation (IP): 15-30 μg using HEK-293T cells over expressing human cPLA2, western blot: 1.5-3 μg/mL using extracts of HEK-293T cells over expressing human cPLA2
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PLA2G4A(5321)
General description
Download the CofA, SDS and IFU specific to your product lot and format
Fragment mixture prepared by cleavage of λDNA with Hind III.
The product is also available as DNA Molecular Weight Marker II, Digoxigenin-labeled.
Size Range: 0.12 to 23.1 kbp
Contents
Ready-to-use solution, 250 μg/mL, in TE buffer (Tris-HCl, 1 mM EDTA, pH 8.0)
Fragment mixture prepared by cleavage of λDNA with Hind III.
The product is also available as DNA Molecular Weight Marker II, Digoxigenin-labeled.
Size Range: 0.12 to 23.1 kbp
Contents
Ready-to-use solution, 250 μg/mL, in TE buffer (Tris-HCl, 1 mM EDTA, pH 8.0)
CPLA2/PLA2G4A (phospholipase A2, group IVA(cytosolic, calcium-dependent)) is located on human chromosome 1q31.1. cPLA2α is an 85 kDa protein made of 749 amino acids. It is a member of the the α-β hydrolase family. CPLA2 has an N-terminal C2 domain (Ca2+ - dependent, phospholipid binding) and two catalytic domains (α/β hydrolase). This protein is located in the cytoplasm.
Application
Anti-Phospholipase A2 (cPLA2) (N-terminal) antibody produced in rabbit may be used in immunoblotting and immunoprecipitation.
Biochem/physiol Actions
Anti-Phospholipase A2 (cPLA2) (N-terminal), specifically recognizes human cPLA2.
CPLA2/PLA2G4A (phospholipase A2, group IVA(cytosolic, calcium-dependent)) helps to hydrolyze phospholipids at the sn-2-acyl ester bond to generate free fatty acid and lysophospholipid second messengers. It is associated with several diseases like cardiovascular disease, diabetes, asthma and arthritis.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
Preparation Note
Store at −20 °C. For continuous use, the product may be stored at 2–8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
PLA2G4A (phospholipase A2, group IVA (cytosolic, calcium-dependent))
Linkous A and Yazlovitskaya E
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2010)
Sangita Paul et al.
eNeuro, 9(6) (2022-11-10)
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