跳转至内容
Merck
CN

SAB4200221

Anti-GrpL/GADS antibody, Mouse monoclonal

clone UW40, purified from hybridoma cell culture

别名:

Anti-GRAP2, Anti-GRB2-related adaptor protein 2, Anti-GRB2-related protein with insert domain, Anti-GRB2L, Anti-GRBLG, Anti-GRBX, Anti-GRF40, Anti-GRID, Anti-GRPL, Anti-Growth factor receptor-bound protein 2-related adaptor protein 2, Anti-Hematopoietic cell-associated adapter protein GrpL, Anti-Mona, Anti-P38, GRB-2-like protein, Anti-RP3-370M22.1, Anti-SH3-SH2-SH3 adapter Mona

登录 查看组织和合同定价。

选择尺寸

关于此项目

UNSPSC Code:
12352203
NACRES:
NA.44
MDL number:
MFCD03455450
Conjugate:
unconjugated
Clone:
UW40, monoclonal
Application:
FACS, IP, WB
Citations:
2

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

biological source

mouse

conjugate

unconjugated

antibody form

purified from hybridoma cell culture

antibody product type

primary antibodies

clone

UW40, monoclonal

form

buffered aqueous solution

mol wt

antigen ~41 kDa

species reactivity

human, mouse

concentration

~1.0 mg/mL

technique(s)

flow cytometry: suitable, immunoprecipitation (IP): suitable, western blot: 0.5-1.0 μg/mL using whole extracts of human Jurkat cells

isotype

IgG2a

UniProt accession no.

O75791

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GRAP2(9402)

General description

GrpL is a SH2- and SH3-domain containing adaptor protein that regulates tyrosine kinase signaling in leukocytes. This adaptor protein associates with SLP-76 and subsequently enhances NF-AT activation in T cells. GrpL also interacts with gab-1 . Monoclonal Anti-GrpL/GADS antibody is specific for human and mouse GrpL.

Immunogen

fusion protein expressing human GrpL.

Application

Monoclonal Anti-GrpL/GADS antibody is suitable for use in western blot (0.5-1.0 μg/mL using whole extracts of human Jurkat cells), immunoprecipitation and flow cytometry.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品？  

试试我们的产品选型工具.

wgk

WGK 1

存储类别

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000141289
0000137217
080M4835

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

C L Law et al.
The Journal of experimental medicine, 189(8), 1243-1253 (1999-04-20)
Propagation of signals from the T cell antigen receptor (TCR) involves a number of adaptor molecules. SH2 domain-containing protein 76 (SLP-76) interacts with the guanine nucleotide exchange factor Vav to activate the nuclear factor of activated cells (NF-AT), and its
M Qiu et al.
Biochemical and biophysical research communications, 253(2), 443-447 (1999-01-08)
The SH2- and SH3-containing adaptor molecules serve to recruit cytosolic signal-transducing molecules to the activated receptor tyrosine kinases. In this study, we report the molecular cloning of a novel adaptor-like protein, Grap-2 (Grb-2 related adaptor protein 2), using the multisubstrate

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持