SAB4200231
Anti-DCAL-1 antibody, Mouse monoclonal
clone UW50, purified from hybridoma cell culture
别名:
Anti-C-type lectin-like 1, Anti-CLECL1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
UW50, monoclonal
Application:
FACS
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
UW50, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
flow cytometry: 0.25-0.50 μg/test using 1x106 human Raji cells
isotype
IgM
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CLECL1(160365)
General description
Dendritic cell-associated lectin-1 (DCAL-1), also known as C-type lectin-like-1 (CLECL1), is a novel C-type lectin-like molecule, encoded by the gene mapped to human chromosome 12p13.31. The encoded protein is exclusively expressed in human hematopoietic cells, in particular at high levels in dendritic cells (DCs) and B cells.
Monoclonal Anti-DCAL-1 (mouse IgM isotype) is derived from the hybridoma UW50 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice, immunized with a human DCAL-1 fusion protein
Immunogen
human DCAL-1 fusion protein.
Application
Monoclonal Anti-DCAL-1 antibody produced in mouse may be used in flow cytometry.
Biochem/physiol Actions
Dendritic cell-associated lectin-1 (DCAL-1) functions as a T-cell co-stimulatory molecule and increases interleukin-4 secretion. The encoded protein is also implicated in the regulation of the immune response.
Monoclonal Anti-DCAL-1 recognizes human DCAL-1.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Preparation Note
For continuous use, store at 2-8°C for up to one month. For extended storage, freeze at -20°C in working aliquots. Repeated freezing and thawing,or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.
Ryan EJ
Journal of Immunology, 169, 5638-5648 (2002)
Elizabeth J Ryan et al.
Human immunology, 70(1), 1-5 (2008-11-26)
Dendritic cell-associated lectin-1 (DCAL-1), also known as C-type lectin-like-1 (CLECL1), is a novel C-type lectin-like molecule expressed by antigen presenting cells including dendritic cells (DCs). Here we report that incubation of immature DCs (iDCs) with an anti-DCAL-1 monoclonal antibody (mAb)
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