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Merck
CN

SAB4200350

Sigma-Aldrich

Anti-ALS2 (C-terminal) antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody

别名:

Anti-ALS2CR6, Anti-ALSJ, Anti-Alsin, Anti-IAHSP, Anti-PLSJ

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UNSPSC代码:
12352203
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生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen ~185 kDa (An additional weak band of ~150 kDa may be observed in some cell extracts.)

种属反应性

mouse, rat, human

浓度

~1.5 mg/mL

技术

indirect immunofluorescence: 1-2 μg/mL using NIH3T3 cells
western blot: 1.5-3.0 μg/mL using HEK-293T cell lysates over-expressing human ALS2 or rat cerebellum extracts (S1 fraction).

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... ALS2(57679)
mouse ... Als2(74018)
rat ... Als2(363235)

免疫原

synthetic peptide corresponding to a sequence near the C-terminal region of rat ALS2, conjugated to KLH. The corresponding sequence is identical in mouse and highly conserved (single amino acid substitution) in human ALS2.

外形

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
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分析证书(COA)

Lot/Batch Number

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So Morishita et al.
FEBS letters, 593(2), 230-241 (2018-11-30)
Macropinocytosis is a nonspecific bulk uptake of extracellular fluid. During endosome maturation, the Rab5-to-Rab7 switch machinery executes the conversion from early to late endosomes. However, how the Rab switch works during macropinosome maturation remains unclear. Here, we elucidate the Rab

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