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Merck
CN

SAB4200368

Sigma-Aldrich

Anti-LRIG3 antibody, Mouse monoclonal

clone LRG3-3, purified from hybridoma cell culture

别名:

Monoclonal Anti-LRIG3 antibody produced in mouse, Anti-FLJ90440, Anti-KIAA3016, Anti-leucine-rich repeats and immunoglobulin-like domains 3

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

mouse

偶联物

unconjugated

抗体形式

purified from hybridoma cell culture

抗体产品类型

primary antibodies

克隆

LRG3-3, monoclonal

表单

buffered aqueous solution

分子量

antigen ~125 kDa

种属反应性

human

浓度

~1.0 mg/mL

技术

flow cytometry: suitable
indirect immunofluorescence: suitable
western blot: 1.0-2.0 μg/mL using extracts of H1395 cells

同位素/亚型

IgG1

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... LRIG3(121227)

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一般描述

Monoclonal Anti-LRIG3 (mouse IgG1 isotype) is derived from the hybridoma LRG3-3 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a peptide corresponding to a sequence at the N-terminus human LRIG3 conjugated to KLH. Leucine-rich and immunoglobulin-like domain 3 (LRIG3) belongs to the family of LRIG. LRIG3 mRNA is widely expressed, with the highest levels in the stomach, skin and thyroid.

免疫原

a peptide corresponding to a sequence at the N-terminus human LRIG3, conjugated to KLH. The corresponding sequence is identical in monkey and share high homology with rat and mouse LRIG3.

应用

Monoclonal Anti-LRIG3 antibody produced in mouse has been used in:
  • immunoblotting
  • immunofluorescence
  • flow cytometry (FACS)

生化/生理作用

Leucine-rich and immunoglobulin-like domain 3 (LRIG3) is implicated in tumorigenesis, psoriasis, neural crest development and complex tissue morphogenesis. LRIG3 interacts with the ErbB family of receptors and Netrin 1.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea
Guo D, et al.
Genomics, 84(1), 157-165 (2004)
Victoria E Abraira et al.
PloS one, 5(2), e8981-e8981 (2010-02-04)
The Lrig genes encode a family of transmembrane proteins that have been implicated in tumorigenesis, psoriasis, neural crest development, and complex tissue morphogenesis. Whether these diverse phenotypes reflect a single underlying cellular mechanism is not known. However, Lrig proteins contain

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