SAB4200368
Anti-LRIG3 antibody, Mouse monoclonal
clone LRG3-3, purified from hybridoma cell culture
别名:
Monoclonal Anti-LRIG3 antibody produced in mouse, Anti-FLJ90440, Anti-KIAA3016, Anti-leucine-rich repeats and immunoglobulin-like domains 3
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
LRG3-3, monoclonal
Application:
FACS, IF, WB
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
LRG3-3, monoclonal
form
buffered aqueous solution
mol wt
antigen ~125 kDa
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
flow cytometry: suitable, indirect immunofluorescence: suitable, western blot: 1.0-2.0 μg/mL using extracts of H1395 cells
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... LRIG3(121227)
General description
Monoclonal Anti-LRIG3 (mouse IgG1 isotype) is derived from the hybridoma LRG3-3 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a peptide corresponding to a sequence at the N-terminus human LRIG3 conjugated to KLH. Leucine-rich and immunoglobulin-like domain 3 (LRIG3) belongs to the family of LRIG. LRIG3 mRNA is widely expressed, with the highest levels in the stomach, skin and thyroid.
Immunogen
a peptide corresponding to a sequence at the N-terminus human LRIG3, conjugated to KLH. The corresponding sequence is identical in monkey and share high homology with rat and mouse LRIG3.
Application
Monoclonal Anti-LRIG3 antibody produced in mouse has been used in:
- immunoblotting
- immunofluorescence
- flow cytometry (FACS)
Biochem/physiol Actions
Leucine-rich and immunoglobulin-like domain 3 (LRIG3) is implicated in tumorigenesis, psoriasis, neural crest development and complex tissue morphogenesis. LRIG3 interacts with the ErbB family of receptors and Netrin 1.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea
Guo D, et al.
Genomics, 84(1), 157-165 (2004)
Victoria E Abraira et al.
PloS one, 5(2), e8981-e8981 (2010-02-04)
The Lrig genes encode a family of transmembrane proteins that have been implicated in tumorigenesis, psoriasis, neural crest development, and complex tissue morphogenesis. Whether these diverse phenotypes reflect a single underlying cellular mechanism is not known. However, Lrig proteins contain
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