Anti-ARG1 antibody, Mouse monoclonal

Monoclonal Anti-ARG1 (mouse IgG2b isotype) is derived from the hybridoma ARG1-6 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide. The type I isoform encoded by the ARG1 gene is a cytosolic enzyme expressed predominantly in the liver as a component of the urea cycle. Arginase 1 (ARG1) gene is mapped on the human chromosome at 6q23.2. Two transcript variants encoding different isoforms have been found for this gene.

synthetic peptide corresponding to an internal region of human ARG1, conjugated to KLH. The corresponding sequence differs by 3 amino acids in rat and by 4 amino acids in mouse ARG1.

Monoclonal Anti-ATG101 antibody produced in mouse is suitable for use in immunoblotting and immunoprecipitation.

Arginase 1 (ARG1) plays a role in removing nitrogen by catalyzing the hydrolysis of arginine to urea and ornithine. Deficiency of this enzyme is associated with argininemia, an inherited autosomal recessive disorder characterized by hyperammonemia.

Monoclonal Anti- ARG1, clone ARG1-6 recognizes human ARG1.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

For continuous use, store at 2-8°C for up to one month. For extended storage, freeze at -20°C in working aliquots. Repeated freezing and thawing,or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

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