Anti-CNTNAP2 (C-terminal) antibody produced in rabbit

Contactin associated protein-like 2 (CNTNAP2) is a member of the contactin-associated protein family. It is co-localized with Shaker-like K⁺ channels in the juxtaparanodal region in myelinated axons. CNTNAP2 is mapped on the human chromosome at 7q35-q36.1.

synthetic peptide corresponding to the C-terminal region of mouse CNTNAP2

Anti-CNTNAP2 (C-terminal) antibody produced in rabbit may be used in immunoblotting and immunoprecipitation.

Anti-CNTNAP2 (C-terminal) recognizes mouse and rat CNTNAP2.

Contactin associated protein-like 2 (CNTNAP2) mediates interactions between neurons and glia during nervous system development and is also involved in the localization of potassium channels within differentiating axons. Mutations in the CNTNAP2 gene is associated with autism spectrum disorder (ASD). CNTNAP2 gene mutations also lead to cortical dysplasia-focal epilepsy syndrome (CDFE) and Gilles de la Tourette syndrome.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

For continuous use, store at -20 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

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