SAB4300105
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-HDACL1 antibody produced in rabbit, Anti-RPD3 antibody produced in rabbit, Anti-histone deacetylase 8 antibody produced in rabbit
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p)
Citations:
-
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~42 kDa
species reactivity
human
concentration
1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200
isotype
IgG
immunogen sequence
(R-A-SP-M-V)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer39)
Gene Information
human ... HDAC8(55869)
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General description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen
Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V), according to the protein HDAC8.
Features and Benefits
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Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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