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Merck
CN

SAB4300252

Sigma-Aldrich

Anti-phospho-SMAD2 (pThr220) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-JV18 antibody produced in rabbit, Anti-JV18-1 antibody produced in rabbit, Anti-MADH2 antibody produced in rabbit, Anti-MADR2 antibody produced in rabbit, Anti-SMAD family member 2 antibody produced in rabbit

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41

主要文件

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生物来源

rabbit

质量水平

100

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

~60 kDa

种属反应性

mouse, human, rat

浓度

1 mg/mL

技术

western blot: 1:500-1:1000

同位素/亚型

IgG

免疫原序列

(P-E-TP-P-P)

NCBI登记号

NP_001003652.1

UniProt登记号

Q15796

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

phosphorylation (pThr220)

基因信息

human ... SMAD2(4087)

一般描述

Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.

免疫原

Peptide sequence around phosphorylation site of threonine 220 (P-E-T(p)-P-P), according to the protein SMAD2.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
951411323

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Feng Dong et al.
Canadian journal of physiology and pharmacology, 96(1), 1-7 (2017-02-09)
Epithelial-to-mesenchymal transition is a cellular process associated with cancer invasion and metastasis. However, the antimetastatic effects of chimaphilin remain elusive. In this study, we attempted to investigate the potential use of chimaphilin as an inhibitor of TGF-β1-induced epithelial-to-mesenchymal transition in
Peng Li et al.
Stem cell research & therapy, 10(1), 144-144 (2019-05-23)
Non-small cell lung cancer (NSCLC) is the second most prevalent cause of cancer-related fatality. Long non-coding RNAs (lncRNAs) have been observed to exercise functions in NSCLC. Here, the current study aimed to explore the potential mechanism of lncRNA MBNL1-AS1 in

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