SAB4300283
Anti-phospho-CBL (pTyr700) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-C-CBL antibody produced in rabbit, Anti-CBL2 antibody produced in rabbit, Anti-Cas-Br-M (murine) ecotropic retroviral transforming sequence antibody produced in rabbit, Anti-RNF55 antibody produced in rabbit
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
~120 kDa
种属反应性
human
浓度
1 mg/mL
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同位素/亚型
IgG
免疫原序列
(T-E-YP-M-T)
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
phosphorylation (pTyr700)
基因信息
human ... CBL(867)
一般描述
Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.
免疫原
Peptide sequence around phosphorylation site of tyrosine 770 (T-E-Y(p)-M-T), according to the protein CBL.
特点和优势
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外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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