SAB4300561
Anti-SMAD1 (Ab-465) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-BSP1 antibody produced in rabbit, Anti-JV4-1 antibody produced in rabbit, Anti-JV41 antibody produced in rabbit, Anti-MADH1 antibody produced in rabbit, Anti-SMAD family member 1 antibody produced in rabbit
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
~55 kDa
种属反应性
mouse, rat, human
浓度
1 mg/mL
技术
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同位素/亚型
IgG
免疫原序列
(I-S-S-V-S)
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SMAD1(4086)
一般描述
Smad1 (SMAD family member 1) is a transcriptional activator, that is located on chromosome 4q31.
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
免疫原
Peptide sequence around aa. 461-465 (I-S-S-V-S), according to the protein SMAD1.
生化/生理作用
SMAD1 (SMAD family member 1) protein has a major role in disease development, hence it acts as a biologic prognostic factor in diseases. The miR-345 repress the multiplication, invasion and migration of prostate cancer by downregulating Smad1.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia
Witkowska M, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(3) (2017)
MiR-345 suppresses proliferation, migration and invasion by targeting Smad1 in human prostate cancer
Chen QG, et al.
Journal of Cancer Research and Clinical Oncology, 142(1), 213-224 (2016)
An interstitial 4q31.21q31.22 microdeletion associated with developmental delay: case report and literature review
Vlaikou AM, et al.
Cytogenetic and genome research, 142(4), 227-238 (2014)
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
Fuentealba LC, et al.
Cell, 131(5), 980-993 (2007)
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