Anti-VEGFR2 (Ab-1059) antibody produced in rabbit

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi′s sarcoma lesions

The antibody detects endogenous levels of total VEGFR2 protein.

Peptide sequence around aa. 1057-1061 (P-D-Y-V-R), according to the protein NP_002244.1

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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