SAB4300676
Anti-Vimentin Antibody
rabbit polyclonal
别名:
Anti-FLJ36605, Anti-VIM
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
monkey, mouse, human, rat
Citations:
6
Technique(s):
western blot: 1:500-1:1000
产品名称
Anti-Vimentin antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~57 kDa
species reactivity
monkey, mouse, human, rat
concentration
1 mg/mL
technique(s)
western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(G-Q-V-I-N)
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... Vimentin(7431)
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
General description
Vimentin is a specific type III intermediate filament (IF) protein. It is abundantly expressed in mesenchymal cells. It is located on human chromosome 10p13.
The antibody detects endogenous level of total Vimentin protein.
The antibody detects endogenous level of total Vimentin protein.
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.
Biochem/physiol Actions
Vimentin helps to preserve the structure of cell and stability of tissue in mesenchymal cells. It is involved in tumorigenesis, EMT (epithelial mesenchymal transition) and the metastatic spread of cancer. It also controls infectious internalization of human papillomavirus 16 pseudovirions.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Immunogen
Peptide sequence around aa. 452-456 (G-Q-V-I-N), according to the protein NP_003371.2
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Vimentin Modulates Infectious Internalization of Human Papillomavirus 16 Pseudovirions
Schafer G, et al.
Journal of Virology (2017)
Viscoelastic properties of vimentin compared with other filamentous biopolymer networks
Janmey PA, et al.
The Journal of Cell Biology (1991)
The gene encoding human vimentin is located on the short arm of chromosome 10
Ferrari S, et al.
American Journal of Human Genetics (1987)
Esther Natalia Muñoz et al.
Biochemistry and biophysics reports, 27, 101027-101027 (2021-06-24)
ROCK2 is a protein involved in the restructuring of the cytoskeleton in cell adhesion and contractibility processes. miR-138-5p and miR-455-3p regulate Rock2 expression, cell proliferation, migration, and invasion in different experimental cell models. However, their participation in the cytoarchitecture and
Vimentin is a potential prognostic factor for tongue squamous cell carcinoma among five epithelial-mesenchymal transition-related proteins
Liu PF, et al.
PLoS ONE (2017)
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