SAB4500169
Anti-CD3EAP antibody produced in rabbit
affinity isolated antibody
别名:
Anti-sense to ERCC-1 protein, ASE-1, CD3-ε-associated protein, DNA-directed RNA polymerase I subunit RPA34, RNA polymerase I-associated factor PAF49
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 54 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000, western blot: 1:500-1:1000
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... RPA34(10849)
General description
The CD3EAP (CD3e molecule, epsilon-associated protein) gene is mapped to human chromosome 19q13.3. It encodes a DNA-dependent RNA polymerase I subunit RPA34 (replication protein A34). This protein is localized to the nucleolus, in the fibrillar centers during interphase and the nucleolus organizer regions of the chromosomes during cell division. Anti-CD3EAP antibody detects endogenous levels of total CD3EAP protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human CD3EAP.
Immunogen Range: 441-490
Immunogen Range: 441-490
Biochem/physiol Actions
The CD3EAP (CD3e molecule, epsilon-associated protein) gene participates in the process of programmed cell death and ribosomal RNA transcription. CD3EAP expression is implicated in the pathogenesis of non-small cell lung cancer (NSCLC).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
19p13. 3-GADD45B common variants and 19q13. 3-PPP1R13L and 19q13. 3-CD3EAP in lung cancer risk among Chinese
Hou W, et al.
Chemico-Biological Interactions, 277, 74-78 (2017)
Effects of PPP1R13L and CD3EAP variants on lung cancer susceptibility among nonsmoking Chinese women
Yin J, et al.
Gene, 524(2), 228-231 (2013)
Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment
Zhang G, et al.
International Journal of Oncology, 52(6), 2155-2165 (2018)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB4500169-100UG | 04061835710010 |