生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 87 kDa
种属反应性
human, mouse, rat
浓度
~1 mg/mL
技术
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... FAP(2191)
一般描述
成纤维细胞活化蛋白1（FAP-1）是一种膜相关蛋白酪氨酸磷酸酶。它由ezrin样细胞骨架结合结构域，六个PSD95/Dlg/Z-1同源（PDZ）结构域和亮氨酸拉链基序组成。FAP-1基因位于人染色体4q21.3。抗-FAP-1抗体检测内源性总FAP-1蛋白水平。
免疫原
该抗血清是针对衍生自人FAP-1的合成肽而生成的。
免疫原范围： 331-380
免疫原范围： 331-380
应用
兔抗FAP-1抗体可用于蛋白质印迹分析（1：500）和免疫组织化学（10 μg/ml）。
生化/生理作用
成纤维细胞活化蛋白1（FAP-1）参与肿瘤发生，细胞凋亡，癌症进展和胰岛素信号传导。它可作为高级别浆液性卵巢癌和乳腺癌的预后标志物。FAP-1基因的过表达与几种人类癌症有关，例如肝细胞癌，胰腺癌，卵巢癌，血液学和结肠癌。FAP-1基因的突变会导致肝癌和肺癌。
特点和优势
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
外形
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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