产品名称
抗-FAP-1 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 87 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... FAP(2191)
Application
兔抗FAP-1抗体可用于蛋白质印迹分析（1：500）和免疫组织化学（10 μg/ml）。
Biochem/physiol Actions
成纤维细胞活化蛋白1（FAP-1）参与肿瘤发生，细胞凋亡，癌症进展和胰岛素信号传导。它可作为高级别浆液性卵巢癌和乳腺癌的预后标志物。FAP-1基因的过表达与几种人类癌症有关，例如肝细胞癌，胰腺癌，卵巢癌，血液学和结肠癌。FAP-1基因的突变会导致肝癌和肺癌。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
General description
成纤维细胞活化蛋白1（FAP-1）是一种膜相关蛋白酪氨酸磷酸酶。它由ezrin样细胞骨架结合结构域，六个PSD95/Dlg/Z-1同源（PDZ）结构域和亮氨酸拉链基序组成。FAP-1基因位于人染色体4q21.3。抗-FAP-1抗体检测内源性总FAP-1蛋白水平。
Immunogen
该抗血清是针对衍生自人FAP-1的合成肽而生成的。
免疫原范围： 331-380
免疫原范围： 331-380
Physical form
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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