biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 44 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... OPN3(23596)
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General description
Anti-OPN3 Antibody detects endogenous levels of total OPN3 protein.
Opsin 3 (OPN3) is also termed as encephalopsin or panopsin. It is a member of the encephalopsin/tmt-opsin subfamily. It is expressed in brain, liver, placenta, heart and pancreatic tissues. The OPN3 gene is located on human chromosome 1q43.
Immunogen
The antiserum was produced against synthesized peptide derived from human OPN3.
Immunogen Range: 161-210
Immunogen Range: 161-210
Biochem/physiol Actions
Opsin3 controls the apoptotic pathway and makes hepatocellular carcinoma cells fragile to 5-fluorouracil treatment. OPN3 plays an important role in oncogenesis and drug resistance. It also plays crucial roles in various physiological and pathological processes.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Multiple hits for the association of uterine fibroids on human chromosome 1q43.
Aissani B, et al.
PLoS ONE, 8(3), e58399-e58399 (2013)
Encephalopsin (OPN3) protein abundance in the adult mouse brain.
Nissila J, et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 198(11), 833-839 (2012)
Curcumin alleviated oxidation stress injury by mediating osteopontin in nephrolithiasis rats.
Huang, et al.
Acta Cirurgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa em Cirurgia, 38, e380223-e380223 (2023)
Bioinformatic Analysis of Human OPN3 Alternative Promoters Associated with Cancer.
Al-Obaide MA, et al.
Applied Mathematics & Information Sciences, 10, 1223-1229 (2016)
Opsin3 sensitizes hepatocellular carcinoma cells to 5-fluorouracil treatment by regulating the apoptotic pathway.
Jiao J, et al.
Cancer Letters, 320(1), 96-103 (2012)
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