Quality Level
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 52 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HNF4A(3172)
General description
Anti-HNF4 Antibody detects endogenous levels of total HNF4 protein.
Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor, located on human chromosome 20q13.12.
Immunogen
The antiserum was produced against synthesized peptide derived from human HNF4 alpha.
Immunogen Range: 280-329
Immunogen Range: 280-329
Biochem/physiol Actions
Hepatocyte nuclear factor 4 alpha (HNF4α) plays an important role in the growth of liver. Mutations in HNF4α results in maturity onset diabetes of the young (MODY).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Direct induction of hepatocyte-like cells from immortalized human bone marrow mesenchymal stem cells by overexpression of HNF4α.
Hu X, et al.
Biochemical and Biophysical Research Communications, 478(2), 791-797 (2016)
The Common p.R114W HNF4A Mutation Causes a Distinct Clinical Subtype of Monogenic Diabetes.
Laver TW, et al.
Diabetes, 65(10), 3212-3217 (2016)
Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population.
Lin WH, et al.
Diabetologia, 49(6), 1214-1221 (2006)
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