产品名称
Anti-Integrin β1 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 88 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGB1(3688)
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General description
Anti-Integrin β1 Antibody detects endogenous levels of total Integrin β1 protein.
Integrinβ1 is a mechanosensor, that is located on human chromosome 10p11.22. It is present in normal cells and tumor-associated cells.
Immunogen
The antiserum was produced against synthesized peptide derived from human Integrin beta1.
Immunogen Range: 749-798
Immunogen Range: 749-798
Application
Anti-integrin β1, C-terminal antibody has been used in immunophenotyping of separated cells.
Biochem/physiol Actions
Integrin β1 acts as an adhesive molecule in the development of de novo focal contact, keratinocyte migration and re-epithelialization of wound tissue.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
β1 Integrin as a Prognostic and Predictive Marker in Triple-Negative Breast Cancer.
Yin HL, et al.
International Journal of Molecular Sciences, 17(9), 1432-1432 (2016)
Evaluation of mesenchymal stem cells in treatment of infertility in male rats.
Hassan AI and Alam SS
Stem Cell Research & Therapy, 5(6), 131-131 (2014)
Genomic aberrations associated with erlotinib resistance in non-small cell lung cancer cells.
Serizawa M, et al.
Anticancer Research, 33(12), 5223-5233 (2013)
β1 integrin signaling in asymmetric migration of keratinocytes under mechanical stretch in a co-cultured wound repair model.
Lu D, et al.
BioMedical Engineering OnLine, 15(2), 130-130 (2016)
The Effect of Mesenchymal Stem Cells and Chitosan Gel on Full Thickness Skin Wound Healing in Albino Rats: Histological, Immunohistochemical and Fluorescent Study.
El Sadik AO, et al.
PLoS ONE, 10(9) (2015)
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