SAB4501584
Anti-CD18 antibody produced in rabbit
affinity isolated antibody
别名:
95 β, CD18, cell surface adhesion glycoproteins LFA- 1/CR3/p150, complement receptor C3 β, integrin β-2
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 84 kDa
种属反应性
human, rat, mouse
浓度
~1 mg/mL
技术
ELISA: 1:1000
immunofluorescence: 1:100-1:500
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ITGB2(3689)
一般描述
Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
CD18/ ITGB2 (integrin subunit β2) is also termed as Mac-1 or complement receptor 3. The ITGB2 gene is mapped to human chromosome 21q22.3. It is mainly expressed in blood. Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
CD18/ ITGB2 (integrin subunit β2) is also termed as Mac-1 or complement receptor 3. The ITGB2 gene is mapped to human chromosome 21q22.3. It is mainly expressed in blood. Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human CD18/ITGB2.
Immunogen Range: 720-769
Immunogen Range: 720-769
生化/生理作用
CD18/ ITGB2 (integrin subunit β 2) plays an important role in the progression and function of T-cells. Mutations in ITGB2 results in leukocyte adhesion deficiency type 1, which has an established role in T-cell development and function. ITGB2/CD18 is associated with chronic colitis.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Use of degenerate oligonucleotide primed PCR (DOP-PCR) for the genotyping of low-concentration DNA samples.
Barbaux S, et al.
Journal of Molecular Medicine, 79(5-6), 329-332 (2001)
Evaluating a CLL susceptibility variant in ITGB2 in families with multiple subtypes of hematological malignancies.
Nicholas BB, et al.
Blood, 130(1), 86?88-86?88 (2017)
Altered levels of soluble CD18 may associate immune mechanisms with outcome in sepsis.
Kragstrup TW, et al.
Clinical and Experimental Immunology, 190(2), 258-267 (2017)
The ITGB2 immunomodulatory gene (CD18), enterocolitis, and Hirschsprung's disease.
Moore SW, et al.
Journal of Pediatric Surgery, 43(8), 1439-1444 (2008)
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