SAB4501584
Anti-CD18 antibody produced in rabbit
affinity isolated antibody
别名:
95 β, CD18, cell surface adhesion glycoproteins LFA- 1/CR3/p150, complement receptor C3 β, integrin β-2
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关于此项目
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 84 kDa
species reactivity
human, rat, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ITGB2(3689)
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General description
Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
CD18/ ITGB2 (integrin subunit β2) is also termed as Mac-1 or complement receptor 3. The ITGB2 gene is mapped to human chromosome 21q22.3. It is mainly expressed in blood. Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
CD18/ ITGB2 (integrin subunit β2) is also termed as Mac-1 or complement receptor 3. The ITGB2 gene is mapped to human chromosome 21q22.3. It is mainly expressed in blood. Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human CD18/ITGB2.
Immunogen Range: 720-769
Immunogen Range: 720-769
Biochem/physiol Actions
CD18/ ITGB2 (integrin subunit β 2) plays an important role in the progression and function of T-cells. Mutations in ITGB2 results in leukocyte adhesion deficiency type 1, which has an established role in T-cell development and function. ITGB2/CD18 is associated with chronic colitis.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Use of degenerate oligonucleotide primed PCR (DOP-PCR) for the genotyping of low-concentration DNA samples.
Barbaux S, et al.
Journal of Molecular Medicine, 79(5-6), 329-332 (2001)
Altered levels of soluble CD18 may associate immune mechanisms with outcome in sepsis.
Kragstrup TW, et al.
Clinical and Experimental Immunology, 190(2), 258-267 (2017)
Evaluating a CLL susceptibility variant in ITGB2 in families with multiple subtypes of hematological malignancies.
Nicholas BB, et al.
Blood, 130(1), 86?88-86?88 (2017)
The ITGB2 immunomodulatory gene (CD18), enterocolitis, and Hirschsprung's disease.
Moore SW, et al.
Journal of Pediatric Surgery, 43(8), 1439-1444 (2008)
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