biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 35 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TAS2R10(50839)
General description
Anti-TAS2R10 antibody detects endogenous levels of total TAS2R10 protein.
The TAS2R10 (taste 2 receptor member 10) gene belongs to G-protein coupled receptors family. The receptor is particularly expressed in the tongue and palate epithelium.
Immunogen
The antiserum was produced against synthesized peptide derived from human TAS2R10.
Immunogen Range: 122-171
Immunogen Range: 122-171
Biochem/physiol Actions
The gene TAS2R10 (taste 2 receptor member 10) encodes a human bitter taste receptor that is induced by bitter compounds. TAS2R10 is known to be stimulated by toxic strychnine and many other compounds, such as sesquiterpene lactones, the alkaloid strychnine, and the synthetic denatonium benzoate. Overexpression of TAS2R10 might prevent the stemness, invasion and migration of cancer cells.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
The receptors and coding logic for bitter taste.
Mueller KL
Nature, 434(7030), 225-229 (2005)
Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1?.
Nicholas DA
PLoS ONE, 12(5), 1-24 (2017)
Stephan Born et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(1), 201-213 (2013-01-04)
Bitter taste is a basic taste modality, required to safeguard animals against consuming toxic substances. Bitter compounds are recognized by G-protein-coupled bitter taste receptors (TAS2Rs). The human TAS2R10 responds to the toxic strychnine and numerous other compounds. The mechanism underlying