SAB4503695
Anti-GASP1 antibody produced in rabbit
affinity isolated antibody
别名:
G-protein coupled receptor-associated sorting protein 1, GASP, GASP-1, GPRASP1, KIAA0443
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 156 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GASP1(9737)
General description
Anti-GASP1 Antibody detects endogenous levels of total GASP1 protein.
G-protein coupled receptor-associated sorting protein 1 (GASP-1) is expressed at high level in the olfactory bulb, hippocampus, hypothalamus and some thalamic and cortical regions. It is located on human chromosome Xq22. It is also termed as WFIKKNRP or WFIKKN2. GASP-1 has a whey acidic protein domain, a follistatin/Kazal domain, an Ig domain, two tandem Kunitz domains and a netrin domain.
Immunogen
The antiserum was produced against synthesized peptide derived from human GASP1.
Immunogen Range: 741-790
Immunogen Range: 741-790
Biochem/physiol Actions
G-protein coupled receptor-associated sorting protein 1 (GASP-1) acts as a ubiquitous tumor marker. It plays an important role in the post endocytic sorting process. It is also expected to play a major role in recycling and degradation of several G-protein-coupled receptors (GPCRs).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1
Martini L, et al.
Faseb Journal, 21(3), 802-811 (2007)
Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
Lee YS and Lee SJ
Proceedings of the National Academy of Sciences of the USA (2013)
Impaired striatum-dependent behavior in GASP-1-knock-out mice
Mathis C, et al.
Genes, Brain, and Behavior, 10(3), 299-308 (2011)
G-protein coupled receptor-associated sorting protein 1 (GASP-1), a ubiquitous tumor marker
Zheng X, et al.
Experiments in Microbial Genetics, 93(1), 111-115 (2012)
A novel Xq22.1 deletion in a male with multiple congenital abnormalities and respiratory failure
Cao Y and Aypar U
European Journal of Medical Genetics, 59(5), 274-277 (2016)
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