Product Name
Monoclonal Anti-SOX2 antibody produced in mouse, clone 10F10, ascites fluid
生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
10F10, monoclonal
分子量
34 kDa
种属反应性
human
技术
direct ELISA: 1:10,000
immunohistochemistry: 1:200-1:1,000
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000
同位素/亚型
IgG1
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SOX2(20674)
一般描述
SOX2 (sex-determining region Y-box 2) is a transcription factor consisting of 317 amino acids. It has an HMG (high mobility group box) domain and is a critical transcription regulator of normal stem cell. It is located on human chromosome 3q26.3.
免疫原
Purified recombinant fragment of human SOX2 expressed in E.coli.
Mouse monoclonal antibody raised against SOX2
Mouse monoclonal antibody raised against SOX2
应用
Monoclonal Anti-SOX2 antibody has been used as a core pluripotency factor to regulate stem cell pluripotency.
生化/生理作用
SOX2 (sex-determining region Y-box 2) down-regulation reduces the stem cell count, that affects breast cancer cells in initiating tumor progression. It participates in chemoresistance and regular lung cancer therapies. In mouse, SOX2 plays an important role in branching morphogenesis and regulating lung epithelial cell differentiation.
外形
Ascitic fluid containing 0.03% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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