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NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
RMH01, monoclonal, recombinant monoclonal
Technique(s):
capture ELISA: 0.1-2 μg/mL, western blot: 0.1-1 μg/mL
Application:
ELISA (c), WB
Citations:
4
recombinant
expressed in HEK 293 cells
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RMH01, monoclonal, recombinant monoclonal
form
buffered aqueous glycerol solution
technique(s)
capture ELISA: 0.1-2 μg/mL, western blot: 0.1-1 μg/mL
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
六组氨酸标签(His-tag)由四到六个通过基因融合的组氨酸组成。它被广泛用于通过固定化金属离子亲和层析(IMAC)对蛋白进行纯化。
Immunogen
在N端带有6xHis标签的肽与在C端带有6xHis标签的另一种肽的混合物。
Biochem/physiol Actions
该抗体是一种人兔嵌合抗体,是通过将兔抗His标签单克隆抗体(RM146)的抗原结合区(重链和轻链的可变域、VH和VL的可变域)与人IgG1的恒定域融合而制成的。该抗体仅可被抗人IgG二抗识别。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多信息。
Physical form
溶于含有50%甘油、1%BSA和0.09%叠氮化钠的磷酸盐缓冲盐水中。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 2
法规信息
常规特殊物品
低风险生物材料
此项目有
Jonathan F Lovell et al.
BMC medicine, 20(1), 462-462 (2022-11-30)
Numerous vaccine strategies are being advanced to control SARS-CoV-2, the cause of the COVID-19 pandemic. EuCorVac-19 (ECV19) is a recombinant protein nanoparticle vaccine that displays the SARS-CoV-2 receptor-binding domain (RBD) on immunogenic nanoliposomes. Initial study of a phase 2 randomized
Tandem immobilized metal-ion affinity chromatography/immunoaffinity purification of His-tagged proteins?evaluation of two anti-His-tag monoclonal antibodies
Muller KM, et al.
Analytical Biochemistry, 259(1), 54-61 (1998)
Loree Heller et al.
Journal of cellular and molecular medicine, 24(15), 8772-8778 (2020-07-02)
In neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, multiple sclerosis and amyotrophic lateral sclerosis, neuroinflammation can lead to blood-brain barrier (BBB) breakdown. After intravenous or intra-arterial injection into mice, endothelial progenitor cells (EPCs) home to the damaged BBB to
Reynald Thinard et al.
Pharmaceutics, 14(7) (2022-07-28)
The failures of anti-β-amyloid immunotherapies suggested that the very low fraction of injected antibodies reaching the brain parenchyma due to the filtering effect of the BBB may be a reason for the lack of therapeutic effect. However, there is no
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