SAB5600106
Anti-Phospho-AMPA Receptor antibody, GluR 1 subunit (Ser845), Rabbit Monoclonal
recombinant, expressed in HEK 293 cells, clone RM296, purified immunoglobulin
别名:
Glutamate Receptor 1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
RM296, monoclonal, recombinant monoclonal
Species reactivity:
human
Application:
IHC, WB
Citations:
3
recombinant
expressed in HEK 293 cells
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RM296, monoclonal, recombinant monoclonal
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
immunohistochemistry: 1:100-1:200, western blot: 1:100-1:200
isotype
IgG
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer845)
Quality Level
Gene Information
human ... GRIA1(2890)
General description
GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is located on human chromosome 5q33.2. It is expressed mainly in brain areas.
Immunogen
A phospho-peptide corresponding to human Phospho-Glutamate Receptor 1 (GluR1) (Ser845).
Biochem/physiol Actions
GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It is associated with migraine.
This antibody reacts to human Glutamate Receptor 1, AMPA Receptor (GluR1) only when phosphorylated at Ser845. There is no cross-reactivity to GluR1 that is not phosphorylated at Ser845. This antibody may also react to mouse or rat Phospho-AMPA Receptor (GluR1) (Ser845) as predicted by immunogen homology.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility
Formicola D, et al.
BMC Medical Genetics, 11(1), 103-103 (2010)
Selective disruption of stimulus-reward learning in glutamate receptor gria1 knock-out mice
Mead AN and Stephens DN
The Journal of Neuroscience, 23(3), 1041-1048 (2003)
Functional organization of the GluR1 glutamate receptor promoter
Borges K and Dingledine R
The Journal of Biological Chemistry, 276(28), 25929-25938 (2001)
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