SAB5600114
Anti-CD140b (PDGF Receptor beta)antibody, Rabbit Monoclonal
recombinant, expressed in HEK 293 cells, clone RM303, purified immunoglobulin
别名:
Platelet-derived growth factor receptor beta
产品名称
Anti-CD140b (PDGF Receptor beta)antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM303, purified immunoglobulin
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RM303, monoclonal
recombinant monoclonal
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
immunohistochemistry: 1:500-1:1000
western blot: 1:250-1:500
isotype
IgG
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PDGFRB(5159)
Biochem/physiol Actions
PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.
This antibody reacts to human CD140b (PDGFR-beta) (Platelet-derived growth factor receptor beta).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.
Immunogen
A peptide corresponding to the C-terminus of human CD140b.
Physical form
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
A genome-wide map of aberrantly expressed chromosomal islands in colorectal cancer.
Staub E, et al.
Molecular Cancer, 5(1), 37-37 (2006)
PDGFRB gain-of-function mutations in sporadic infantile myofibromatosis.
Arts FA
Human Molecular Genetics, 26(10), 1801-1810 (2017)
Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.
Liu F
Oncotarget, 8(13), 22059-22075 (2017)
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