biological source
rabbit
conjugate
unconjugated
material
colorless
clone
8F3P7, monoclonal
form
liquid
mol wt
34 kDa
species reactivity
rat, human, rat
concentration
1.3 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
QTIVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYRE
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... STX4(6810)
Application
WB, IF/ICC
General description
Plasma membrane t-SNARE that mediates docking of transport vesicles (By similarity. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane (By similarity. In neurons, recruited at neurite tips to membrane domains rich in the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC which promotes neurite tip surface expression of the dopamine transporter SLC6A3/DAT by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones (By similarity.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Syntaxin 4 (Q12846).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
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