SAB5702938
Anti-Human IgG Antibody, clone 1U6H0, Rabbit Monoclonal
别名:
immunoglobulin heavy constant gamma 1 (G1m marker)
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关于此项目
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1U6H0, monoclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
human
Citations:
Technique(s):
immunohistochemistry: 1:50 - 1:300
western blot: 1:500 - 1:2000
western blot: 1:500 - 1:2000
Uniprot accession no.:
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
1U6H0, monoclonal
form
liquid
mol wt
50 kDa
species reactivity
human
concentration
0.23 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:300
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... IGHG1(3500)
Application
WB, IHC
General description
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.
Immunogen
Human IgG
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
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