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SAB6010005

Anti-phospho-MAPT (S404) antibody, clone 11H10, Rabbit Monoclonal

Name: Anti-phospho-MAPT (S404) antibody, clone 11H10, Rabbit Monoclonal
Brand: SIGMA

recombinant, expressed in HEK293F cells

别名:

Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau), MAPT, MAPTL MTBT1 TAU

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

Conjugate:

unconjugated

Clone:

11H10, recombinant monoclonal

Application:

ELISA, FACS, IF, IHC

Citations:

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属性

recombinant

expressed in HEK 293 F cells

Quality Level

100

conjugate

unconjugated

antibody product type

primary antibodies

clone

11H10, recombinant monoclonal

form

liquid

mol wt

150 kDa

purified by

affinity chromatography

species reactivity

human

concentration

0.4mg/ml

technique(s)

ELISA: 2000:10000, flow cytometry: 1:50-1:200, immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200

isotype

IgG

UniProt accession no.

P10636

shipped in

wet ice

storage temp.

-10 to -25°C

target post-translational modification

phosphorylation (pSer404)

说明

General description

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Immunogen

A synthesized peptide derived from Human MAPT

Physical form

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Preparation Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Other Notes

ST-pS-PS

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c