SAB6010047
Anti-phospho-PPP2CA (Y307) antibody, clone 3F11, Rabbit Monoclonal
recombinant, expressed in HEK293F cells
别名:
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA
重组
expressed in HEK 293 F cells
质量水平
偶联物
unconjugated
抗体产品类型
primary antibodies
克隆
3F11, recombinant monoclonal
表单
liquid
分子量
150 kDa
纯化方式
affinity chromatography
种属反应性
human
浓度
0.5mg/ml
技术
ELISA: 2000:10000
flow cytometry: 1:50-1:200
immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
同位素/亚型
IgG
UniProt登记号
运输
wet ice
储存温度
-10 to -25°C
靶向翻译后修饰
phosphorylation (pTyr307), phosphorylation (pTyr307)
一般描述
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at ′Ser-259′.
免疫原
A synthesized peptide derived from human Phospho-PPP2CA (Y307)
外形
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
制备说明
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
其他说明
PD-pY-FL
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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