SAB6010091
Anti-phospho-MAPT (S324) antibody, clone 4E8, Rabbit Monoclonal
recombinant, expressed in HEK293F cells
别名:
Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU
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UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
4E8, recombinant monoclonal
Application:
ELISA, FACS, IF, IHC
Citations:
-
recombinant
expressed in HEK 293 F cells
conjugate
unconjugated
antibody product type
primary antibodies
clone
4E8, recombinant monoclonal
form
liquid
mol wt
150 kDa
purified by
affinity chromatography
species reactivity
human
concentration
0.525mg/ml
technique(s)
ELISA: 2000:10000, flow cytometry: 1:50-1:200, immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
-10 to -25°C
target post-translational modification
phosphorylation (pSer324)
Quality Level
General description
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Immunogen
A synthesized peptide derived from human Phospho-MAPT (S324)
Physical form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Preparation Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Other Notes
KG-pS-LK
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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