SAB6010096
Anti-phospho-LAT (Y191) antibody, clone 2E4, Rabbit Monoclonal
recombinant, expressed in HEK293F cells
别名:
Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
2E4, recombinant monoclonal
Application:
ELISA, FACS, IF, IHC
Citations:
-
recombinant
expressed in HEK 293 F cells
conjugate
unconjugated
antibody product type
primary antibodies
clone
2E4, recombinant monoclonal
form
liquid
mol wt
150 kDa
purified by
affinity chromatography
species reactivity
human
concentration
2.35mg/ml
technique(s)
ELISA: 2000:10000, flow cytometry: 1:50-1:200, immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
-10 to -25°C
Quality Level
target post-translational modification
phosphorylation (pTyr191)
General description
Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Immunogen
A synthesized peptide derived from human Phospho-LAT (Y191)
Physical form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Preparation Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Other Notes
SRE-pY-VN
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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