SAB6012249
Anti-phospho-c-Myc (Thr58) Antibody, clone 24GB230, Rabbit Monoclonal


clone 24GB230, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
BHLHe39, C-Myc, MRTL, MYCC
生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
24GB230, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
51 kDa
种属反应性
human
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
0.8 mg/ml
技术
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
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运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MYC(4609)
一般描述
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 51-65 of human Phospho-c-Myc (T58) [NP_002458.2].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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