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Merck
CN

SBR00086

Remdesivir

≥98% (HPLC), powder

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关于此项目

经验公式(希尔记法):
C27H35N6O8P
化学文摘社编号:
分子量:
602.58
UNSPSC Code:
51101500
NACRES:
NA.41
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InChI

1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1

InChI key

RWWYLEGWBNMMLJ-YSOARWBDSA-N

SMILES string

CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4

assay

≥98% (HPLC)

form

powder

color

white to off-white

antibiotic activity spectrum

viruses

mode of action

DNA synthesis | inhibits

shipped in

ambient

Quality Level

General description

Remdesiviris is an antibioitic which belongs to the class of compounds known as nucleotide analogues. Remdesivir has broad spectrum antiviral activity against RNA viruses.

Biochem/physiol Actions

Remdesivir inhibits viral RNA synthesis, which is essential for the replication of RNA viruses. Remdesivir is a nucleotide analogue, which means that it is designed to mimic the structure of natural nucleotides, the building blocks of RNA and DNA. When remdesivir is incorporated into the viral RNA by the viral RNA polymerase, it terminates RNA synthesis prematurely, preventing further replication of the viral RNA. This leads to the inhibition of viral replication and the reduction of viral load, which can help to reduce the severity of viral infections. Remdesivir has been shown to be active against a broad range of RNA viruses, including coronaviruses, filoviruses, and paramyxoviruses, among others.

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

STOT RE 2 Oral

target_organs

Kidney

存储类别

11 - Combustible Solids

wgk

WGK 3

法规信息

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Lot/Batch Number

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