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Merck
CN

SBR00086

Sigma-Aldrich

Remdesivir

≥98% (HPLC), powder

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关于此项目

经验公式(希尔记法):
C27H35N6O8P
化学文摘社编号:
分子量:
602.58
UNSPSC代码:
51101500
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质量水平

方案

≥98% (HPLC)

表单

powder

颜色

white to off-white

抗生素抗菌谱

viruses

作用机制

DNA synthesis | inhibits

运输

ambient

SMILES字符串

CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4

InChI

1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1

InChI key

RWWYLEGWBNMMLJ-YSOARWBDSA-N

一般描述

Remdesiviris is an antibioitic which belongs to the class of compounds known as nucleotide analogues. Remdesivir has broad spectrum antiviral activity against RNA viruses.

生化/生理作用

Remdesivir inhibits viral RNA synthesis, which is essential for the replication of RNA viruses. Remdesivir is a nucleotide analogue, which means that it is designed to mimic the structure of natural nucleotides, the building blocks of RNA and DNA. When remdesivir is incorporated into the viral RNA by the viral RNA polymerase, it terminates RNA synthesis prematurely, preventing further replication of the viral RNA. This leads to the inhibition of viral replication and the reduction of viral load, which can help to reduce the severity of viral infections. Remdesivir has been shown to be active against a broad range of RNA viruses, including coronaviruses, filoviruses, and paramyxoviruses, among others.

象形图

Health hazard

警示用语:

Warning

危险声明

预防措施声明

危险分类

STOT RE 2 Oral

靶器官

Kidney

储存分类代码

11 - Combustible Solids

WGK

WGK 3

法规信息

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