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关于此项目
经验公式（希尔记法）:
C11H13BrN2O5
化学文摘社编号:
分子量:
333.14
UNSPSC Code:
51101500
MDL number:
NACRES:
NA.21
InChI key
ODZBBRURCPAEIQ-PIXDULNESA-N
InChI
1S/C11H13BrN2O5/c12-2-1-6-4-14(11(18)13-10(6)17)9-3-7(16)8(5-15)19-9/h1-2,4,7-9,15-16H,3,5H2,(H,13,17,18)/b2-1+/t7-,8+,9+/m0/s1
SMILES string
O=C(C(/C=C/Br)=CN1[C@H]2C[C@H](O)[C@@H](CO)O2)NC1=O
assay
≥95%
antibiotic activity spectrum
viruses
mode of action
enzyme | inhibits
shipped in
ambient
storage temp.
2-8°C
Quality Level
General description
Brivudine is a synthetic nucleoside analogue antibiotic. It has structural similarities to the natural nucleoside deoxyuridine.
Application
Brivudine has bee used: - in the research of pancreatic cancer
Biochem/physiol Actions
Mode of Action: Brivudine blocks the action of DNA polymerases, inhibiting viral replication.
Antimicrobial Spectrum: Active against Varicella zoster virus and Herpes simplex virus
Antimicrobial Spectrum: Active against Varicella zoster virus and Herpes simplex virus
Features and Benefits
High quality antibiotic suitable for mulitple research applications Commonly used in Cell Biology and Biochemical applications
法规信息
新产品
此项目有
Jörg-Christian Heinrich et al.
Journal of cancer research and clinical oncology, 137(9), 1349-1361 (2011-08-13)
Several reports describe the importance of the chaperone HSP27 (HSPB1) in cancer progression, and the demand for drugs that modulate HSPB1-activity is increasing rapidly. We reported earlier that RP101 (Bromovinyldeoxyuridine, BVDU, Brivudine) improves the efficacy of chemotherapy in pancreatic cancer.
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