SMB00100
Bavachinin
≥95% (LC/MS-ELSD)
别名:
4′-Hydroxy-7-methoxy-6-(3-methyl-2-butenyl)flavanone, 7-O-Methylbavachin, Bavachinin A
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关于此项目
经验公式（希尔记法）:
C21H22O4
化学文摘社编号:
分子量:
338.40
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
产品名称
Bavachinin, ≥95% (LC/MS-ELSD)
InChI
1S/C21H22O4/c1-13(2)4-5-15-10-17-18(23)11-20(14-6-8-16(22)9-7-14)25-21(17)12-19(15)24-3/h4,6-10,12,20,22H,5,11H2,1-3H3/t20-/m0/s1
SMILES string
COc1cc2O[C@@H](CC(=O)c2cc1C\C=C(\C)C)c3ccc(O)cc3
InChI key
VOCGSQHKPZSIKB-FQEVSTJZSA-N
assay
≥95% (LC/MS-ELSD)
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
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General description
Natural product derived from plant source.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Xiumin Chen et al.
FEBS letters, 587(18), 2930-2935 (2013-08-03)
Spontaneous aggregation of Aβ is a key factor in the development of Alzheimer's disease. In searching for Aβ aggregation inhibitors from traditional Chinese herbal medicines, we identified two active compounds from Psoraleae Fructus, namely isobavachalcone and bavachinin. We further demonstrated
Manoj Nepal et al.
European journal of pharmacology, 691(1-3), 28-37 (2012-07-05)
Hypoxia-inducible factor-1 (HIF-1) consists of two subunits, the HIF-1β, which is constitutively expressed, and HIF-1α, which is oxygen-responsive. HIF-1α is over-expressed in response to hypoxia, increasing transcriptional activity linked to tumor progression, angiogenesis, metastasis, and invasion. This study aimed to
Hiroyuki Haraguchi et al.
Phytotherapy research : PTR, 16(6), 539-544 (2002-09-19)
A meroterpene and four flavonoids were isolated from the seeds of Psoralea corylifolia as antioxidative components. Their structures were elucidated by spectral data and identified as bakuchiol (1), bavachinin (2), bavachin (3), isobavachin (4) and isobavachalcone (5). In particular, meroterpene
Jianmei Luo et al.
Journal of bioscience and bioengineering, 117(2), 191-196 (2013-09-10)
Biotransformation of bavachinin (1) was investigated using three fungal cell cultures of Aspergillus flavus ATCC 30899, Cunninghamella elegans CICC 40250 and Penicillium raistrickii ATCC 10490, respectively. Two major converted products were identified by LC/MS, (1)H NMR and (13)C NMR and
Ming Hong Lee et al.
Biological & pharmaceutical bulletin, 28(12), 2253-2257 (2005-12-06)
The overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) switches the function of NO from a physiological neuromodulator to a neurotoxic effector in central nervous system (CNS) after brain injury. From the methanol extracts of Psoralea corylifolia
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