SMB00207
Cornuside
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关于此项目
经验公式（希尔记法）:
C24H30O14
化学文摘社编号:
分子量:
542.49
NACRES:
NA.25
UNSPSC Code:
12352200
MDL number:
InChI
1S/C24H30O14/c1-3-11-12(4-5-35-21(32)10-6-14(26)17(28)15(27)7-10)13(22(33)34-2)9-36-23(11)38-24-20(31)19(30)18(29)16(8-25)37-24/h3,6-7,9,11-12,16,18-20,23-31H,1,4-5,8H2,2H3/t11-,12+,16+,18+,19-,20+,23+,24-/m0/s1
InChI key
SMTKSCGLXONVGL-ZEIULZLQSA-N
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
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General description
Natural product derived from plant source.
Biochem/physiol Actions
Cornuside is a secoiridoid glucoside with anti-inflammatory properties through the downregulation of iNOS and COX-2 via NF-kB inhibition.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Wang-Lin Jiang et al.
Planta medica, 75(6), 614-619 (2009-03-06)
This study was conducted to investigate the efficacy of cornuside, a secoiridoid glucoside compound, in cultured macrophages as well as in an experimental model of sepsis induced by cecal ligation and puncture (CLP) in rats. Cornuside was added to cultured
Yun Ho Choi et al.
Biological & pharmaceutical bulletin, 34(7), 959-966 (2011-07-02)
Cornuside, a secoiridoid glucoside compound, was isolated from the fruit of Cornus officinalis SIEB. et ZUCC. Cornuside has been reported to possess immunomodulatory and anti-inflammatory activities. However, the effects and mechanism of action of cornuside in inflammation have not been
Wang-Lin Jiang et al.
Pharmacology, 84(3), 162-170 (2009-08-22)
Cornuside, a secoiridoid glucoside compound, was isolated from the fruit of Cornus officinalis Sieb. et Zucc. The present study elucidates the effects of cornuside on cultured rat cortical neuron damage induced by oxygen-glucose deprivation. The results show that cornuside treatment
Dae Gill Kang et al.
Biological & pharmaceutical bulletin, 30(9), 1796-1799 (2007-09-11)
Cornuside is a bisiridoid glucoside compound isolated from the fruit of Cornus officinalis SIEB. et ZUCC. The present study was designed to examine the effects of cornuside on expression levels of cytokine-induced proinflammatory and adhesion molecules in the human umbilical
S P Zhao et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 27(11), 845-848 (1992-01-01)
A new bisiridoid glucoside named cornuside was isolated from the fruits of Cornus officinalis Sieb et Zucc. The structure of cornuside has been established by spectroscopic methods (IR, MS, 1HNMR, 13CNMR).
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