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Merck
CN

SMB00207

Cornuside

≥95% (LC/MS-ELSD)

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关于此项目

经验公式(希尔记法):
C24H30O14
化学文摘社编号:
分子量:
542.49
NACRES:
NA.25
UNSPSC Code:
12352200
MDL number:
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assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C24H30O14/c1-3-11-12(4-5-35-21(32)10-6-14(26)17(28)15(27)7-10)13(22(33)34-2)9-36-23(11)38-24-20(31)19(30)18(29)16(8-25)37-24/h3,6-7,9,11-12,16,18-20,23-31H,1,4-5,8H2,2H3/t11-,12+,16+,18+,19-,20+,23+,24-/m0/s1

InChI key

SMTKSCGLXONVGL-ZEIULZLQSA-N

General description

Natural product derived from plant source.

Biochem/physiol Actions

Cornuside is a secoiridoid glucoside with anti-inflammatory properties through the downregulation of iNOS and COX-2 via NF-kB inhibition.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Shun Zong Song et al.
Bioscience, biotechnology, and biochemistry, 75(4), 656-661 (2011-04-23)
This study elucidated the effects of cornuside on carbon tetrachloride (CCl₄)-induced hepatotoxicity. Rats were treated intraperitoneally with 0.5 mL/kg of CCl₄. Sixteen h after CCl₄ treatment, the levels of serum aminotransferases, tumor necrosis factor-α (TNF-α), and lipid peroxidation were significantly
S P Zhao et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 27(11), 845-848 (1992-01-01)
A new bisiridoid glucoside named cornuside was isolated from the fruits of Cornus officinalis Sieb et Zucc. The structure of cornuside has been established by spectroscopic methods (IR, MS, 1HNMR, 13CNMR).
Wang-Lin Jiang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(4), 266-271 (2010-08-27)
Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis SIEB. et ZUCC. In this study, we investigated the anti-myocardial ischemia and reperfusion (I/R) injury effects of cornuside in vivo and elucidated the potential mechanism. Rat models of



全球贸易项目编号

货号GTIN
SMB00207-1MG04061826169124