SMB00350
Dehydroandrographolide
≥98% (HPLC)
别名:
(1R-(1a,2a,4aa,5β(E),8aβ))-3-[2-(Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethylidene)-2(3H)-furanone
InChI
1S/C20H28O4/c1-13-4-7-16-19(2,10-8-17(22)20(16,3)12-21)15(13)6-5-14-9-11-24-18(14)23/h5,9,11,15-17,21-22H,1,4,6-8,10,12H2,2-3H3/b14-5+/t15-,16?,17+,19-,20-/m0/s1
InChI key
YIIRVUDGRKEWBV-GJVBFGQCSA-N
SMILES string
OC[C@@]([C@H](O)CC1)(C)C([C@]1(C)[C@H]2C/C=C3C=COC\3=O)CCC2=C
biological source
plant (Andrographis paniculata)
assay
≥98% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
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General description
Dehydroandrographolide is a natural diterpenoid found in Andrographis paniculata.
Biochem/physiol Actions
Dehydroandrographolide possesses activity against hepatitis B virus DNA replication.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Dehydroandrographolide enhances innate immunity of intestinal tract through up-regulation the expression of hBD-2
Xiong W B, et al.
DARU Journal of Pharmaceutical Sciences, 23(1), 37-37 (2015)
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents.
Chen H, et al.
Bioorganic & Medicinal Chemistry Letters, 24(10), 2353-2359 (2014)
Naturally derived anti-hepatitis B virus agents and their mechanism of action
Wu Y H.
World Journal of Gastroenterology, 22(1), 188-188 (2016)
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