SMB00452
水甘草碱
≥95% (HPLC)
别名:
(-)-Tabersonine, (5α,12β,19α)-2,3,6,7-Tetrahydro-aspidospermidine-3-carboxylic acid methyl ester, Tabersonin
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关于此项目
经验公式（希尔记法）:
C21H24N2O2
化学文摘社编号:
分子量:
336.43
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C21H24N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-9,19,22H,3,10-13H2,1-2H3/t19-,20-,21-/m0/s1
SMILES string
COC(C1=C2NC3=CC=CC=C3[C@]24[C@]5([H])[C@](C=CCN5CC4)(CC)C1)=O
InChI key
FNGGIPWAZSFKCN-ACRUOGEOSA-N
assay
≥95% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
General description
Tabersonine is a terpenoid indole alkaloid (TIA) found in Amsonia elliptica.
Biochem/physiol Actions
Tabersonine shows hypotensive, anti-tumor, hypoglycemic, and diuretic activity.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Zerihun Demessie et al.
Phytochemistry, 140, 118-124 (2017-05-10)
Vinca minor is a herbaceous plant from the Apocynaceae family known to produce over 50 monoterpene indole alkaloids (MIAs). These include several biologically active MIAs that have a range of pharmaceutical activities. The present study shows that the MIAs, vincamine
Claire Parage et al.
Plant physiology, 172(3), 1563-1577 (2016-10-01)
Expansion of the biosynthesis of plant specialized metabolites notably results from the massive recruitment of cytochrome P450s that catalyze multiple types of conversion of biosynthetic intermediates. For catalysis, P450s require a two-electron transfer catalyzed by shared cytochrome P450 oxidoreductases (CPRs)
Alison Edge et al.
Planta, 247(1), 155-169 (2017-09-13)
Monoterpenoid indole alkaloids (MIAs) have remarkable biological properties that have led to their medical uses for a variety of human diseases. Mutagenesis has been used to generate plants with new alkaloid profiles and a useful screen for rapid comparison of
Hanqing Wang et al.
Food chemistry, 339, 128111-128111 (2020-11-07)
Licorice is known as a botanical source in medicine and a sweetening agent in food products. Commercial licorice is from the source of wild and cultivated G. uralensis. It was recognized that the material basis of wild and cultivated licorice
Amir Akhgari et al.
Molecules (Basel, Switzerland), 20(12), 22621-22634 (2015-12-24)
Rhazya stricta Decne. (Apocynaceae) contains a large number of terpenoid indole alkaloids (TIAs). This study focused on the composition of alkaloids obtained from transformed hairy root cultures of R. stricta employing ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). In the UPLC-MS analyses
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