跳转至内容
Merck
CN

SMB00606

地红霉素

≥96%

别名:

[9S(R)]-9-脱氧-11-脱氧-9,11-[亚氨[2-(2-甲氧基乙氧基)亚乙基]氧]红霉素；LY-237216

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C42H78N2O14
化学文摘社编号:
62013-04-1
分子量:
835.07
UNSPSC Code:
41116107
PubChem Substance ID:
329825077
MDL number:
MFCD00865041

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

InChI

1S/C42H78N2O14/c1-15-29-42(10,49)37-24(4)32(43-30(56-37)21-52-17-16-50-13)22(2)19-40(8,48)36(58-39-33(45)28(44(11)12)18-23(3)53-39)25(5)34(26(6)38(47)55-29)57-31-20-41(9,51-14)35(46)27(7)54-31/h22-37,39,43,45-46,48-49H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,30-,31+,32+,33-,34+,35+,36-,37-,39+,40-,41+,42-/m1/s1

SMILES string

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C4N[C@@H](COCCOC)OC([C@H]4C)[C@]1(C)O

InChI key

WLOHNSSYAXHWNR-KZYCBHIHSA-N

assay

≥96%

form

powder

storage condition

(Keep container tightly closed in a dry and well-ventilated place.)

color

white to off-white

antibiotic activity spectrum

Gram-negative bacteria

mode of action

protein synthesis | interferes

storage temp.

2-8°C

Quality Level

200

正在寻找类似产品? 访问 产品对比指南

相关类别

Biochem/physiol Actions

Dirithromycin is a macrolide antibiotic. It is a prodrug of erythromycylamine that has outstanding activity against Campylobacter. Dirithromycin is a group 3 agent with respect to its interaction with cytochrome P450 (CYP) isoform 3A4, as it interferes poorly with CYP3A4 in vitro and generally does not alter drug metabolism in vivo.

Packaging

1G

Preparation Note

When dissolving dirithromycin in organic solvents, first purge the solvent with inert gas.

To prepare in aqueous buffer, dirithromycin should first be dissolved in ethanol and then diluted with aqueous buffer. The solution is stable for one day.

Dirithromycin is soluble in ethanol at approximately 20 mg/mL, DMF at approximately 10 mg/mL, and DMSO at approximately 15 mg/mL.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Hazard Classifications

Skin Sens. 1

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

pcodes

P280

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
096M4089V
13160712

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Comparative in vitro activities of new 14-, 15-, and 16-membered macrolides.
Hardy DJ, Hensey DM, Beyer JM, Vojtko C, McDonald EJ, Fernandes PB.
Antimicrobial Agents and Chemotherapy, 32(11), 1710-1719 (1988)
Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin.
Westphal JF
British Journal of Clinical Pharmacology, 50(4), 285-295 (2000)

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持