方案
≥97% (HPLC)
表单
powder
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
−20°C
SMILES字符串
O1C(CC(=O)c3c1cc(c(c3)CC=C(C)C)O)c2ccc(cc2)O
InChI
1S/C20H20O4/c1-12(2)3-4-14-9-16-18(23)11-19(24-20(16)10-17(14)22)13-5-7-15(21)8-6-13/h3,5-10,19,21-22H,4,11H2,1-2H3
InChI key
OAUREGNZECGNQS-UHFFFAOYSA-N
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一般描述
Bavachin is soluble in DMSO at 30 mg/mL. Bavachin is not water soluble.
生化/生理作用
Bavachin is a flavonoid isolated from seeds of Psoralea corylifolia. It is a phytoestrogen that activates ERα and ERβ (EC50s = 320 and 680 nM, respectively), stimulates osteoblast proliferation and differentiation, and prevents bone loss following ovariectomy in rats.
Bavachin is an inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT). The IC50 value of bavachin was reported to be 86.0 μM in ACAT assay system using rat liver microsome.
Bavachin is also reported to increase insulin-induced glucose uptake by differentiated adipocytes and myoblasts.
Bavachin is an inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT). The IC50 value of bavachin was reported to be 86.0 μM in ACAT assay system using rat liver microsome.
Bavachin is also reported to increase insulin-induced glucose uptake by differentiated adipocytes and myoblasts.
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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