SMB01018
Cynaropicrin
≥90% (LC/MS-ELSD)
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关于此项目
经验公式（希尔记法）:
C19H22O6
化学文摘社编号:
分子量:
346.37
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
InChI key
KHSCYOFDKADJDJ-NQLMQOPMSA-N
SMILES string
O1[C@@H]2[C@@H]3[C@@H](C[C@@H](C3=C)O)C(=C)C[C@@H]([C@H]2C(=C)C1=O)OC(=O)C(=C)CO
InChI
1S/C19H22O6/c1-8-5-14(24-18(22)9(2)7-20)16-11(4)19(23)25-17(16)15-10(3)13(21)6-12(8)15/h12-17,20-21H,1-7H2/t12-,13-,14-,15-,16+,17+/m0/s1
biological source
plant
assay
≥90% (LC/MS-ELSD)
form
solid
mol wt
346.37
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
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General description
Cynaropicrin is a sesquiterpene lactone, a bioactive natural compound commonly derived from plants such as Cynara scolymus, Pleiotaxis rugosa, Pseudostifftia kingii, Blumea eriantha, and Scopolia atropoides. Current research indicates that this plant metabolite is an inhibitor and may possess diverse biological activities, including anti-inflammatory, antineoplastic, antispasmodic, anti-hyperlipidemic, anti-trypanosomal, anti-malarial, and antiviral properties.
Application
Cynaropicrin is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Biochem/physiol Actions
Cynaropicrin is a potent activator of the AhR-Nrf2-Nqo1 pathway, making it a potential candidate for preventing UVB-induced photoaging. Additionally, it exhibits pro-apoptotic activity, suggesting its potential as an anticancer agent against certain leukocyte cancer cells such as lymphoma or leukemia. Cynaropicrin has demonstrated in vivo activity against Trypanosoma brucei and exhibits immunomodulatory effects by influencing cytokine release and nitric oxide production while also displaying immunosuppressive properties. Moreover, it has anti-inflammatory effects by inhibiting the production of inflammatory mediators and lymphocyte proliferation, which is achieved through conjugation with sulphydryl groups of target protein(s).
Features and Benefits
- Suitable for Biochemical and Biomedical research
- Versatile and adaptable for wide variety of laboratory and research applications
Other Notes
For additional information on our range of Biochemicals, please complete this form.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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