SMB01039
Murrayafoline A
≥90% (LC/MS-ELSD)
别名:
1-Methoxy-3-methyl-9H-carbazole
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关于此项目
经验公式（希尔记法）:
C14H13NO
化学文摘社编号:
分子量:
211.26
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
产品名称
Murrayafoline A, ≥90% (LC/MS-ELSD)
SMILES string
[nH]1c2c(c3c1cccc3)cc(cc2OC)C
InChI
1S/C14H13NO/c1-9-7-11-10-5-3-4-6-12(10)15-14(11)13(8-9)16-2/h3-8,15H,1-2H3
InChI key
HDETUOZJFUNSKG-UHFFFAOYSA-N
biological source
plant
assay
≥90% (LC/MS-ELSD)
form
solid
mol wt
211.26
solubility
water: slightly soluble
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
Application
Murrayafoline A is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Biochem/physiol Actions
Murrayafoline A may be a potential chemotherapeutic agent for use in the treatment of colon cancer and may be useful in preventing the progression of vascular complications such as restenosis.
Features and Benefits
- Suitable for Biochemical and Biomedical research
- Versatile and adaptable for wide variety of laboratory and research applications
General description
Murrayafoline A, a carbazole alkaloid, is a bioactive natural compound commonly derived from plants such as Murraya euchrestifolia, Murraya kwangsiensis, Clausena excavata, Clausena dunniana, and Glycosmis stenocarpa. Current research indicates that this plant metabolite is an inhibitor and may possess diverse biological activities, including anticancer, antimalarial, cardioprotective and antifungal properties.
Other Notes
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 4 - Carc. 2 - Muta. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Hyuk Choi et al.
Biochemical and biophysical research communications, 391(1), 915-920 (2009-12-08)
Molecular lesions in Wnt/beta-catenin signaling and subsequent up-regulation of beta-catenin response transcription (CRT) occur frequently during the development of colon cancer. To identify small molecules that suppress CRT, we screened natural compounds in a cell-based assay for detection of TOPFalsh
Joo-Hui Han et al.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 19(5), 421-426 (2015-09-04)
The increased potential for vascular smooth muscle cell (VSMC) growth is a key abnormality in the development of atherosclerosis and post-angioplasty restenosis. Abnormally high activity of platelet-derived growth factor (PDGF) is believed to play a central role in the etiology
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