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About This Item
经验公式（希尔记法）:
C21H22FN3O · HCl · xH2O
CAS Number:
分子量:
387.88 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
powder
颜色
white to tan
溶解性
H2O: ≥5 mg/mL (warmed)
创始人
Eli Lilly
储存温度
2-8°C
SMILES字符串
Cl.CN1CCC(CC1)c2c[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc23
InChI
1S/C21H22FN3O.ClH/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15;/h2-7,12-14,23H,8-11H2,1H3,(H,24,26);1H
InChI key
DGPDGAPZTPSHBL-UHFFFAOYSA-N
应用
LY-334370 hydrochloride hydrate may be used to study 5-HT 1F-mediated cell signaling.
生化/生理作用
LY-334370 hydrochloride is a selective 5-HT1F receptor agonist.
LY-334370 modulates the transmission in the mouse trigeminal system and inhibits the neuronal responses within rat Sp5C by inhibiting c-Fos activation. It shows efficacy in aborting migraine attacks.
特点和优势
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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