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Merck
CN

SML0011

VAHA

≥98% (HPLC)

别名:

VAHA, Valproyl hydroxamic acid, VPA-HA

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关于此项目

经验公式(希尔记法):
C8H17NO2
化学文摘社编号:
分子量:
159.23
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

solubility

DMSO: ≥25 mg/mL

storage temp.

2-8°C

SMILES string

CCCC(CCC)C(=O)NO

InChI

1S/C8H17NO2/c1-3-5-7(6-4-2)8(10)9-11/h7,11H,3-6H2,1-2H3,(H,9,10)

InChI key

ROJGIRXXBBBMPL-UHFFFAOYSA-N

Application

VAHA may be used in cell signaling studies.

Biochem/physiol Actions

Hydroxamic acid derivatives of valproic acid exhibit anticonvulsant activity with no teratogenic activity in mouse neural tube defect model. It is effective in the treatment of bipolar disorders.
VAHA (Valproyl hydroxamic acid) is an HDAC inhibitor with less activity than valproic acid against Class I enzymes but much greater Class II activity
VAHA is an HDAC inhibitor

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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