SML0073
松脂醇
≥95% (HPLC)
别名:
(+)-松脂醇, 4,4′-((1S,3aR,4S,6aR)-六氢呋喃[3,4-c]呋喃-1,4-二基)双(2-甲氧基苯酚), 4,4′-[(1S,3aR,4S,6aR)-四氢-1H,3H-呋喃[3,4-c]呋喃-1,4-二基]双(2-甲氧基苯酚) )
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关于此项目
经验公式（希尔记法）:
C20H22O6
化学文摘社编号:
分子量:
358.39
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m0/s1
SMILES string
COc1cc(ccc1O)[C@H]2OC[C@H]3[C@@H]2CO[C@@H]3c4ccc(O)c(OC)c4
InChI key
HGXBRUKMWQGOIE-AFHBHXEDSA-N
assay
≥95% (HPLC)
form
powder
color
white to tan
solubility
DMSO: ≥6 mg/mL
shipped in
wet ice
storage temp.
−20°C
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Application
Pinoresinol may be used in cell signaling studies.
Biochem/physiol Actions
松脂素存在于包括药用植物在内的多种植物中，如水生接骨木、杜仲、安息香属、连翘以及特级初榨橄榄油中。其中的接骨木属广泛分布于欧洲、亚洲和北非，并已在传统医学中作为止痛药、抗病毒药、抗炎药、止血药和利尿药用于瘀伤、骨折和水肿。松脂素可通过引起真菌质膜的损伤而显示出有效的抗真菌特性。它通过抑制TNF-α的产生（很可能是通过抑制NF- κB和AP-1）而发挥出抗氧化和抗炎的作用。
通过抑制TNF-α的产生而发挥出抗氧化和抗炎的作用。
Features and Benefits
This compound is featured on the Cytokine Receptors (Tumor Necrosis Receptor Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
An enantiocomplementary dirigent protein for the enantioselective laccase-catalyzed oxidative coupling of phenols.
Benjamin Pickel et al.
Angewandte Chemie (International ed. in English), 49(1), 202-204 (2009-12-01)
J L Peñalvo et al.
European journal of clinical nutrition, 66(7), 795-798 (2012-05-17)
Lignan-rich diets have been associated with favorable health effects through improved metabolic profile. In this study, we hypothesized that dietary lignan intake could be also associated with childhood obesity. We studied prevalent obesity in relation to lignan intake within the
Hyo-Yeon Kim et al.
Journal of pharmacological sciences, 112(1), 105-112 (2010-01-23)
Forsythiae Fructus is known to have diuretic, anti-bacterial, and anti-inflammatory activities. This study examined the hepatoprotective effects of pinoresinol, a lignan isolated from Forsythiae Fructus, against carbon tetrachloride (CCl(4))-induced liver injury. Mice were treated intraperitoneally with vehicle or pinoresinol (25
Y Fukuhara et al.
Enzyme and microbial technology, 52(1), 38-43 (2012-12-04)
Bacterial genes for the degradation of major dilignols produced in lignifying xylem are expected to be useful tools for the structural modification of lignin in plants. For this purpose, we isolated pinZ involved in the conversion of pinoresinol from Sphingobium
Hyo Won Jung et al.
Neuroscience letters, 480(3), 215-220 (2010-07-06)
The activation of microglia plays an important role in a variety of brain disorders by the excessive production of inflammatory mediators such as nitric oxide (NO), prostaglandin E(2) (PGE(2)) and proinflammatory cytokines. We investigated here whether pinoresinol isolated from the
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